Ontology highlight
ABSTRACT:
SUBMITTER: Kim HI
PROVIDER: S-EPMC2830728 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Kim Hugh I HI Kim Hyungjun H Shin Young Shik YS Beegle Luther W LW Jang Seung Soon SS Neidholdt Evan L EL Goddard William A WA Heath James R JR Kanik Isik I Beauchamp J L JL
Journal of the American Chemical Society 20100201 7
Oxidative stresses from irritants such as hydrogen peroxide and ozone (O(3)) can cause dysfunction of the pulmonary surfactant (PS) layer in the human lung, resulting in chronic diseases of the respiratory tract. For identification of structural changes of pulmonary surfactant protein B (SP-B) due to the heterogeneous reaction with O(3), field-induced droplet ionization (FIDI) mass spectrometry has been utilized. FIDI is a soft ionization method in which ions are extracted from the surface of mi ...[more]