Ontology highlight
ABSTRACT:
SUBMITTER: Dreumont N
PROVIDER: S-EPMC2831310 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Dreumont Natacha N Hardy Sara S Behm-Ansmant Isabelle I Kister Liliane L Branlant Christiane C Stévenin James J Bourgeois Cyril F CF
Nucleic acids research 20091203 4
Alternative splicing is regulated in part by variations in the relative concentrations of a variety of factors, including serine/arginine-rich (SR) proteins. The SR protein SC35 self-regulates its expression by stimulating unproductive splicing events in the 3' untranslated region of its own pre-mRNA. Using various minigene constructs containing the terminal retained intron and flanking exons, we identified in the highly conserved last exon a number of exonic splicing enhancer elements respondin ...[more]