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Efficient production of 2-oxobutyrate from 2-hydroxybutyrate by using whole cells of Pseudomonas stutzeri strain SDM.

ABSTRACT: 2-Oxobutyrate is an important intermediate in the chemical, drug, and food industries. Whole cells of Pseudomonas stutzeri SDM, containing NAD-independent lactate dehydrogenases, effectively converted 2-hydroxybutyrate into 2-oxobutyrate. Under optimal conditions, the biocatalytic process produced 2-oxobutyrate at a high concentration (44.4 g liter(-1)) and a high yield (91.5%).

SUBMITTER: Gao C

PROVIDER: S-EPMC2832366 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature

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Efficient production of 2-oxobutyrate from 2-hydroxybutyrate by using whole cells of Pseudomonas stutzeri strain SDM.

Gao Chao C Zhang Wen W Lv Chuanjuan C Li Lixiang L Ma Cuiqing C Hu Chunhui C Xu Ping P

Applied and environmental microbiology 20100115 5

2-Oxobutyrate is an important intermediate in the chemical, drug, and food industries. Whole cells of Pseudomonas stutzeri SDM, containing NAD-independent lactate dehydrogenases, effectively converted 2-hydroxybutyrate into 2-oxobutyrate. Under optimal conditions, the biocatalytic process produced 2-oxobutyrate at a high concentration (44.4 g liter(-1)) and a high yield (91.5%). ...[more]

PMID: 20080995

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