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Computational analysis identifies human adenovirus type 55 as a re-emergent acute respiratory disease pathogen.


ABSTRACT: Novel human adenoviruses (HAdVs) arise from genome recombination. Analysis of HAdV type 55 from an outbreak in China shows a hexon recombination between HAdV-B11 and HAdV-B14, resulting in a genome that is 97.4% HAdV-B14. Sporadic appearances as a re-emergent pathogen and misidentification as "HAdV-B11a" are due to this partial hexon.

SUBMITTER: Walsh MP 

PROVIDER: S-EPMC2832463 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature

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Computational analysis identifies human adenovirus type 55 as a re-emergent acute respiratory disease pathogen.

Walsh Michael P MP   Seto Jason J   Jones Morris S MS   Chodosh James J   Xu Wenbo W   Seto Donald D  

Journal of clinical microbiology 20091230 3


Novel human adenoviruses (HAdVs) arise from genome recombination. Analysis of HAdV type 55 from an outbreak in China shows a hexon recombination between HAdV-B11 and HAdV-B14, resulting in a genome that is 97.4% HAdV-B14. Sporadic appearances as a re-emergent pathogen and misidentification as "HAdV-B11a" are due to this partial hexon. ...[more]

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