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ABSTRACT:
SUBMITTER: Timofeev VI
PROVIDER: S-EPMC2833031 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Timofeev V I VI Chuprov-Netochin R N RN Samigina V R VR Bezuglov V V VV Miroshnikov K A KA Kuranova I P IP
Acta crystallographica. Section F, Structural biology and crystallization communications 20100223 Pt 3
Attempts to crystallize the noncovalent complex of recombinant human insulin with polysialic acid were carried out under normal and microgravity conditions. Both crystal types belonged to the same space group, I2(1)3, with unit-cell parameters a = b = c = 77.365 A, alpha = beta = gamma = 90.00 degrees. The reported space group and unit-cell parameters are almost identical to those of cubic insulin reported in the PDB. The results of X-ray studies confirmed that the crystals obtained were cubic i ...[more]