Psychobiology and molecular genetics of resilience.
Ontology highlight
ABSTRACT:
SUBMITTER: Feder A
PROVIDER: S-EPMC2833107 | biostudies-literature | 2009 Jun
REPOSITORIES: biostudies-literature
Publications
Psychobiology and molecular genetics of resilience.
Feder Adriana A Nestler Eric J EJ Charney Dennis S DS
Nature reviews. Neuroscience 20090601 6
Every individual experiences stressful life events. In some cases acute or chronic stress leads to depression and other psychiatric disorders, but most people are resilient to such effects. Recent research has begun to identify the environmental, genetic, epigenetic and neural mechanisms that underlie resilience, and has shown that resilience is mediated by adaptive changes in several neural circuits involving numerous neurotransmitter and molecular pathways. These changes shape the functioning ...[more]
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