Ontology highlight
ABSTRACT:
SUBMITTER: Zietman AL
PROVIDER: S-EPMC2834463 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Zietman Anthony L AL Bae Kyounghwa K Slater Jerry D JD Shipley William U WU Efstathiou Jason A JA Coen John J JJ Bush David A DA Lunt Margie M Spiegel Daphna Y DY Skowronski Rafi R Jabola B Rodney BR Rossi Carl J CJ
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100201 7
PURPOSE To test the hypothesis that increasing radiation dose delivered to men with early-stage prostate cancer improves clinical outcomes. PATIENTS AND METHODS Men with T1b-T2b prostate cancer and prostate-specific antigen </= 15 ng/mL were randomly assigned to a total dose of either 70.2 Gray equivalents (GyE; conventional) or 79.2 GyE (high). No patient received androgen suppression therapy with radiation. Local failure (LF), biochemical failure (BF), and overall survival (OS) were outcomes. ...[more]