Ontology highlight
ABSTRACT:
SUBMITTER: Stewart DJ
PROVIDER: S-EPMC2835194 | biostudies-literature | 2009 Jun
REPOSITORIES: biostudies-literature
Stewart Duncan J DJ Kutryk Michael J B MJ Fitchett David D Freeman Michael M Camack Nancy N Su Yinghua Y Della Siega Anthony A Bilodeau Luc L Burton Jeffrey R JR Proulx Guy G Radhakrishnan Sam S
Molecular therapy : the journal of the American Society of Gene Therapy 20090407 6
Despite the promise of proangiogenic gene therapy most clinical trials have failed to show benefit for the primary end point analysis. The NOGA angiogenesis Revascularization Therapy: assessment by RadioNuclide imaging (NORTHERN) trial was a double-blind, placebo-controlled study of intramyocardial vascular endothelial growth factor (VEGF165) gene therapy versus placebo, involving seven sites across Canada, designed to overcome major limitations of previous proangiogenic gene therapy trials. A t ...[more]