Ontology highlight
ABSTRACT:
SUBMITTER: Miranda KC
PROVIDER: S-EPMC2835735 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Miranda Kevin C KC Karet Fiona E FE Brown Dennis D
PloS one 20100310 3
The vacuolar-type H(+)-ATPase (V-ATPase) is a multisubunit proton pump that is involved in both intra- and extracellular acidification processes throughout the body. Multiple homologs and splice variants of V-ATPase subunits are thought to explain its varied spatial and temporal expression pattern in different cell types. Recently subunit nomenclature was standardized with a total of 22 subunit variants identified. However this standardization did not accommodate the existence of splice variants ...[more]