Ontology highlight
ABSTRACT:
SUBMITTER: Ford B
PROVIDER: S-EPMC2838032 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Journal of bacteriology 20100129 7
P pili are extracellular appendages responsible for the targeting of uropathogenic Escherichia coli to the kidney. They are assembled by the chaperone-usher (CU) pathway of pilus biogenesis involving two proteins, the periplasmic chaperone PapD and the outer membrane assembly platform, PapC. Many aspects of the structural biology of the Pap CU pathway have been elucidated, except for the C-terminal domain of the PapC usher, the structure of which is unknown. In this report, we identify a stable ...[more]