Ontology highlight
ABSTRACT:
SUBMITTER: Peng T
PROVIDER: S-EPMC2840343 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Peng Tao T Bonamy Ghislain M C GM Glory-Afshar Estelle E Rines Daniel R DR Chanda Sumit K SK Murphy Robert F RF
Proceedings of the National Academy of Sciences of the United States of America 20100201 7
Many proteins or other biological macromolecules are localized to more than one subcellular structure. The fraction of a protein in different cellular compartments is often measured by colocalization with organelle-specific fluorescent markers, requiring availability of fluorescent probes for each compartment and acquisition of images for each in conjunction with the macromolecule of interest. Alternatively, tailored algorithms allow finding particular regions in images and quantifying the amoun ...[more]