Ontology highlight
ABSTRACT:
SUBMITTER: Osborne AR
PROVIDER: S-EPMC2843544 | biostudies-literature | 2010 May
REPOSITORIES: biostudies-literature
Molecular and biochemical parasitology 20100201 1
During the blood stage of its lifecycle, the malaria parasite resides and replicates inside a membrane vacuole within its host cell, the human erythrocyte. The parasite exports many proteins across the vacuole membrane and into the host cell cytoplasm. Most exported proteins are characterized by the presence of a host targeting (HT) motif, also referred to as a Plasmodium export element (PEXEL), which corresponds to the consensus sequence RxLxE/D/Q. During export the HT motif is cleaved by an un ...[more]