Ontology highlight
ABSTRACT:
SUBMITTER: McDermott DH
PROVIDER: S-EPMC2844018 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
McDermott David H DH Conway Susan E SE Wang Tao T Ricklefs Stacy M SM Agovi Manza A MA Porcella Stephen F SF Tran Huong Thi Bich HT Milford Edgar E Spellman Stephen S Abdi Reza R
Blood 20100112 11
Despite continual improvement, morbidity and mortality after hematopoietic stem cell transplantation (HSCT) remain high. The importance of chemokines in HSCT lies in their regulation of immune responses that determine transplantation outcomes. We investigated the role of recipient and donor chemokine system gene polymorphisms by using a candidate gene approach on the incidence of graft-versus-host disease and posttransplantation outcomes in 1370 extensively human leukocyte antigen-matched, unrel ...[more]