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Nocardia farcinica lung infection in a patient with cystic fibrosis: a case report.

ABSTRACT:

Introduction

Respiratory tract infections are the major causes of morbidity and mortality in patients with cystic fibrosis. Nocardia are rarely implicated in these infections and few reports of the involvement of this species are found in the literature.

Case presentation

We describe a case of lung infection followed by chronic colonization of trimethoprim and sulfamethoxazole resistant Nocardia farcinica in a patient with cystic fibrosis. The chronic colonization of this uncommon bacterium in patients with cystic fibrosis was proved using a newly developed real-time polymerase chain reaction assay, which indicates that this bacterium, despite treatment, is difficult to eradicate.

Conclusion

Our case report confirms that this organism can be recovered in persons with cystic fibrosis. Its eradication is necessary especially if the patient is to undergo lung transplantation.

SUBMITTER: Bittar F

PROVIDER: S-EPMC2844380 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature

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Nocardia farcinica lung infection in a patient with cystic fibrosis: a case report.

Bittar Fadi F Stremler Nathalie N Audié Jean-Pierre JP Dubus Jean-Christophe JC Sarles Jacques J Raoult Didier D Rolain Jean-Marc JM

Journal of medical case reports 20100308

<h4>Introduction</h4>Respiratory tract infections are the major causes of morbidity and mortality in patients with cystic fibrosis. Nocardia are rarely implicated in these infections and few reports of the involvement of this species are found in the literature.<h4>Case presentation</h4>We describe a case of lung infection followed by chronic colonization of trimethoprim and sulfamethoxazole resistant Nocardia farcinica in a patient with cystic fibrosis. The chronic colonization of this uncommon ...[more]

PMID: 20211000

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