Ontology highlight
ABSTRACT:
SUBMITTER: Gung BW
PROVIDER: S-EPMC2844647 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Gung Benjamin W BW Bailey Lauren N LN Wonser Josh J
Tetrahedron letters 20100401 17
In the presence of the N-heterocyclic carbene gold catalyst (NHC-AuIPr, 7), propargyl esters 1a-f and 13 undergo a [4C + 3C] cycloaddition reaction with cyclopentadiene and furan under mild conditions. The evidence suggests the formation of the seven-membered ring occurs by a direct cycloaddition process, rather than a stepwise cyclopropanation/Cope rearrangement sequence. ...[more]