Homeostasis and inflammation in the intestine.
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ABSTRACT:
SUBMITTER: Garrett WS
PROVIDER: S-EPMC2845719 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Publications
Homeostasis and inflammation in the intestine.
Garrett Wendy S WS Gordon Jeffrey I JI Glimcher Laurie H LH
Cell 20100301 6
The gut is home to our largest collection of microbes. The ability of the immune system to coevolve with the microbiota during postnatal life allows the host and microbiota to coexist in a mutually beneficial relationship. Failure to achieve or maintain equilibrium between a host and its microbiota has negative consequences for both intestinal and systemic health. In this Review, we consider the many cellular and molecular methods by which inflammatory responses are regulated to maintain intesti ...[more]
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