Ontology highlight
ABSTRACT:
SUBMITTER: Pettit GR
PROVIDER: S-EPMC2846224 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Pettit George R GR Meng Yanhui Y Pettit Robin K RK Herald Delbert L DL Cichacz Zbigniew A ZA Doubek Dennis L DL Richert Linda L
Journal of natural products 20100301 3
Cancer cell line bioassay-guided separation of an ethyl acetate extract prepared from a plant-associated fungus, Coprinus cinereus, led to the isolation of three new sesquiterpenes, coprinastatin 1 (1), coprinol (2), and the epimer (4a), of the known sesquiterpene triol (4b). The previously described sesquiterpene 3 and oxazolinone 5 were also isolated. The structure and relative configuration of coprinastatin 1 (1) were determined by HRMS and by 1D- and 2D-NMR spectroscopic analyses. The struct ...[more]