Ontology highlight
ABSTRACT:
SUBMITTER: Tang W
PROVIDER: S-EPMC2848899 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Tang Weihua W Harmon Paula P Gulley Margaret L ML Mwansambo Charles C Kazembe Peter N PN Martinson Francis F Wokocha Clifford C Kenney Shannon C SC Hoffman Irving I Sigel Carlie C Maygarden Susan S Hoffman Mariah M Shores Carol C
Clinical cancer research : an official journal of the American Association for Cancer Research 20100316 7
<h4>Purpose</h4>Some EBV-directed therapies are predicted to be effective only when lytic viral replication occurs. We studied whether cyclophosphamide chemotherapy induces EBV to switch from latent to lytic phases of infection in a series of EBV-associated Burkitt lymphomas.<h4>Experimental design</h4>Children with first presentation of an expanding, solid maxillary or mandibular mass consistent with Burkitt lymphoma underwent fine-needle aspiration just prior to the initiation of cyclophospham ...[more]