Ontology highlight
ABSTRACT:
SUBMITTER: Swanson JA
PROVIDER: S-EPMC2851551 | biostudies-literature | 2008 Aug
REPOSITORIES: biostudies-literature
Nature reviews. Molecular cell biology 20080709 8
The ingestion of particles or cells by phagocytosis and of fluids by macropinocytosis requires the formation of large endocytic vacuolar compartments inside cells by the organized movements of membranes and the actin cytoskeleton. Fc-receptor-mediated phagocytosis is guided by the zipper-like progression of local, receptor-initiated responses that conform to particle geometry. By contrast, macropinosomes and some phagosomes form with little or no guidance from receptors. The common organizing st ...[more]