Ontology highlight
ABSTRACT:
SUBMITTER: Jacobs J
PROVIDER: S-EPMC2851993 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Jacobs Joshua J Kahana Michael J MJ Ekstrom Arne D AD Mollison Matthew V MV Fried Itzhak I
Proceedings of the National Academy of Sciences of the United States of America 20100322 14
Finding our way in spatial environments is an essential part of daily life. How do we come to possess this sense of direction? Extensive research points to the hippocampus and entorhinal cortex (EC) as key neural structures underlying spatial navigation. To better understand this system, we examined recordings of single-neuron activity from neurosurgical patients playing a virtual-navigation video game. In addition to place cells, which encode the current virtual location, we describe a unique c ...[more]