Ontology highlight
ABSTRACT:
SUBMITTER: Engelen S
PROVIDER: S-EPMC2853104 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Engelen Stéfan S Tahi Fariza F
Nucleic acids research 20100104 7
Predicting RNA secondary structures is a very important task, and continues to be a challenging problem, even though several methods and algorithms are proposed in the literature. In this article, we propose an algorithm called Tfold, for predicting non-coding RNA secondary structures. Tfold takes as input a RNA sequence for which the secondary structure is searched and a set of aligned homologous sequences. It combines criteria of stability, conservation and covariation in order to search for s ...[more]