Ontology highlight
ABSTRACT:
SUBMITTER: Alam MT
PROVIDER: S-EPMC2853524 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Alam Mohammad T MT Merlo Maria E ME Hodgson David A DA Wellington Elizabeth M H EM Takano Eriko E Breitling Rainer R
BMC genomics 20100326
<h4>Background</h4>The transition from exponential to stationary phase in Streptomyces coelicolor is accompanied by a major metabolic switch and results in a strong activation of secondary metabolism. Here we have explored the underlying reorganization of the metabolome by combining computational predictions based on constraint-based modeling and detailed transcriptomics time course observations.<h4>Results</h4>We reconstructed the stoichiometric matrix of S. coelicolor, including the major anti ...[more]