Ontology highlight
ABSTRACT:
SUBMITTER: Handel AE
PROVIDER: S-EPMC2854120 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Handel Adam E AE Handunnetthi Lahiru L Berlanga Antonio J AJ Watson Corey T CT Morahan Julia M JM Ramagopalan Sreeram V SV
PloS one 20100413 4
<h4>Background</h4>Multiple sclerosis (MS) is a complex neurological disorder. Its aetiology involves both environmental and genetic factors. Recent genome-wide association studies have identified a number of single nucleotide polymorphisms (SNPs) associated with susceptibility to (MS). We investigated whether these genetic variations were associated with alteration in gene expression.<h4>Methods/principal findings</h4>We used a database of mRNA expression and genetic variation derived from immo ...[more]