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The solution structure of (+)-spongistatin 1 in DMSO.


ABSTRACT: The solution structure of (+)-spongistatin 1 (1) has been determined via 1- and 2-D NMR techniques in conjunction with extensive in silico conformational analysis to comprise a mixture of 4 major rapidly interconverting conformational families.

SUBMITTER: Atasoylu O 

PROVIDER: S-EPMC2856070 | biostudies-literature | 2010 Apr

REPOSITORIES: biostudies-literature

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The solution structure of (+)-spongistatin 1 in DMSO.

Atasoylu Onur O   Furst George G   Risatti Christina C   Smith Amos B AB  

Organic letters 20100401 8


The solution structure of (+)-spongistatin 1 (1) has been determined via 1- and 2-D NMR techniques in conjunction with extensive in silico conformational analysis to comprise a mixture of 4 major rapidly interconverting conformational families. ...[more]

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