Ontology highlight
ABSTRACT:
SUBMITTER: Bergen SE
PROVIDER: S-EPMC2859300 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Bergen Sarah E SE Fanous Ayman H AH Kuo Po-Hsiu PH Wormley Brandon K BK O'Neill F Anthony FA Walsh Dermot D Riley Brien P BP Kendler Kenneth S KS
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20100301 2
Robust associations between the dysbindin gene (DTNBP1) and schizophrenia have been demonstrated in many but not all samples, and evidence that this gene particularly predisposes to negative symptoms in this illness has been presented. The current study sought to replicate the previously reported negative symptom associations in an Irish case-control sample. Association between dysbindin and schizophrenia has been established in this cohort, and a factor analysis of the assessed symptoms yielded ...[more]