Ontology highlight
ABSTRACT:
SUBMITTER: Herring BP
PROVIDER: S-EPMC2860107 | biostudies-literature | 2001 Jan
REPOSITORIES: biostudies-literature
Herring B P BP Lyons G E GE Hoggatt A M AM Gallagher P J PJ
American journal of physiology. Cell physiology 20010101 1
Telokin is a 17-kDa protein with an amino acid sequence that is identical to the COOH terminus of the 130-kDa myosin light chain kinase (MLCK). Telokin mRNA is transcribed from a second promoter, located within an intron, in the 3' region of the MLCK gene. In the current study, we show by in situ mRNA hybridization that telokin mRNA is restricted to the smooth muscle cell layers within adult smooth muscle tissues. In situ mRNA analysis of mouse embryos also revealed that telokin expression is re ...[more]