Ontology highlight
ABSTRACT:
SUBMITTER: Zhao J
PROVIDER: S-EPMC2860782 | biostudies-literature | 2009 Dec
REPOSITORIES: biostudies-literature
Zhao Jianhua J Bradfield Jonathan P JP Li Mingyao M Wang Kai K Zhang Haitao H Kim Cecilia E CE Annaiah Kiran K Glessner Joseph T JT Thomas Kelly K Garris Maria M Frackelton Edward C EC Otieno F George FG Shaner Julie L JL Smith Ryan M RM Chiavacci Rosetta M RM Berkowitz Robert I RI Hakonarson Hakon H Grant Struan F A SF
Obesity (Silver Spring, Md.) 20090528 12
The prevalence of obesity in children and adults in the United States has increased dramatically over the past decade. Besides environmental factors, genetic factors are known to play an important role in the pathogenesis of obesity. A number of genetic determinants of adult BMI have already been established through genome-wide association (GWA) studies. In this study, we examined 25 single-nucleotide polymorphisms (SNPs) corresponding to 13 previously reported genomic loci in 6,078 children wit ...[more]