Ontology highlight
ABSTRACT:
SUBMITTER: Cicatiello L
PROVIDER: S-EPMC2861078 | biostudies-literature | 2010 May
REPOSITORIES: biostudies-literature
Cicatiello Luigi L Mutarelli Margherita M Grober Oli M V OM Paris Ornella O Ferraro Lorenzo L Ravo Maria M Tarallo Roberta R Luo Shujun S Schroth Gary P GP Seifert Martin M Zinser Christian C Chiusano Maria Luisa ML Traini Alessandra A De Bortoli Michele M Weisz Alessandro A
The American journal of pathology 20100326 5
Luminal-like breast tumor cells express estrogen receptor alpha (ERalpha), a member of the nuclear receptor family of ligand-activated transcription factors that controls their proliferation, survival, and functional status. To identify the molecular determinants of this hormone-responsive tumor phenotype, a comprehensive genome-wide analysis was performed in estrogen stimulated MCF-7 and ZR-75.1 cells by integrating time-course mRNA expression profiling with global mapping of genomic ERalpha bi ...[more]