Visual proteomics of the human pathogen Leptospira interrogans.
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ABSTRACT:
SUBMITTER: Beck M
PROVIDER: S-EPMC2862215 | biostudies-literature | 2009 Nov
REPOSITORIES: biostudies-literature
Publications
Visual proteomics of the human pathogen Leptospira interrogans.
Beck Martin M Malmström Johan A JA Lange Vinzenz V Schmidt Alexander A Deutsch Eric W EW Aebersold Ruedi R
Nature methods 20091018 11
Systems biology conceptualizes biological systems as dynamic networks of interacting elements, whereby functionally important properties are thought to emerge from the structure of such networks. Owing to the ubiquitous role of complexes of interacting proteins in biological systems, their subunit composition and temporal and spatial arrangement within the cell are of particular interest. 'Visual proteomics' attempts to localize individual macromolecular complexes inside of intact cells by templ ...[more]
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