Ontology highlight
ABSTRACT:
SUBMITTER: Anderson MG
PROVIDER: S-EPMC2862261 | biostudies-literature | 2008 Oct
REPOSITORIES: biostudies-literature
Anderson Michael G MG Hawes Norman L NL Trantow Colleen M CM Chang Bo B John Simon W M SW
Pigment cell & melanoma research 20070628 5
Spontaneous mutations altering mouse coat colors have been a classic resource for discovery of numerous molecular pathways. Although often overlooked, the mouse iris is also densely pigmented and easily observed, thus representing a similarly powerful opportunity for studying pigment cell biology. Here, we present an analysis of iris phenotypes among 16 mouse strains with mutations influencing melanosomes. Many of these strains exhibit biologically and medically relevant phenotypes, including pi ...[more]