Ontology highlight
ABSTRACT:
SUBMITTER: Panaitof SC
PROVIDER: S-EPMC2864722 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Panaitof S Carmen SC Abrahams Brett S BS Dong Hongmei H Geschwind Daniel H DH White Stephanie A SA
The Journal of comparative neurology 20100601 11
Multiple studies, involving distinct clinical populations, implicate contactin associated protein-like 2 (CNTNAP2) in aspects of language development and performance. While CNTNAP2 is broadly distributed in developing rodent brain, it shows a striking gradient of frontal cortical enrichment in developing human brain, consistent with a role in patterning circuits that subserve higher cognition and language. To test the hypothesis that CNTNAP2 may be important for learned vocal communication in ad ...[more]