Subcellular localization of Mitf in monocytic cells.
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ABSTRACT:
SUBMITTER: Lu SY
PROVIDER: S-EPMC2869019 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Publications
Subcellular localization of Mitf in monocytic cells.
Lu Ssu-Yi SY Wan Hsiao-Ching HC Li Mengtao M Lin Yi-Ling YL
Histochemistry and cell biology 20100501 6
Microphthalmia-associated transcription factor (Mitf) is a transcription factor that plays an important role in regulating the development of several cell lineages. The subcellular localization of Mitf is dynamic and is associated with its transcription activity. In this study, we examined factors that affect its subcellular localization in cells derived from the monocytic lineage since Mitf is present abundantly in these cells. We identified a domain encoded by Mitf exon 1B1b to be important fo ...[more]
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