Direct determination of molecular haplotypes by chromosome microdissection.
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ABSTRACT:
SUBMITTER: Ma L
PROVIDER: S-EPMC2871314 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Publications
Direct determination of molecular haplotypes by chromosome microdissection.
Ma Li L Xiao Yan Y Huang Hui H Wang Qingwei Q Rao Weinian W Feng Yue Y Zhang Kui K Song Qing Q
Nature methods 20100321 4
Direct observation of haplotypes is still technically challenging. Here we report a method for the determination of haplotypes through chromosome microdissection. We determined human long-range chromosomal haplotypes with more than 98.85% accuracy at 24,245 genome-wide heterozygous single-nucleotide polymorphism (SNP) loci. ...[more]
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