Ontology highlight
ABSTRACT:
SUBMITTER: Solomon BD
PROVIDER: S-EPMC2871973 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Solomon Benjamin D BD Pineda-Alvarez Daniel E DE Raam Manu S MS Cummings Derek A T DA
Human genetics 20100406 6
VACTERL/VATER association is typically a sporadic disorder. We present data on inheritance in 78 probands with VACTERL association, and show that 9% of probands have a primary relative with at least one component feature of VACTERL association. The prevalence of component features in first-degree relatives is significantly higher than expected in the general population, which has implications for counseling of affected families and for research into possible etiologies. ...[more]