Magnetization transfer imaging, white matter hyperintensities, brain atrophy and slower gait in older men and women.
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ABSTRACT:
SUBMITTER: Rosano C
PROVIDER: S-EPMC2873052 | biostudies-literature | 2010 Jul
REPOSITORIES: biostudies-literature
Publications
Magnetization transfer imaging, white matter hyperintensities, brain atrophy and slower gait in older men and women.
Rosano Caterina C Rosano Caterina C Sigurdsson Sigurdur S Siggeirsdottir Kristin K Phillips Caroline L CL Garcia Melissa M Jonsson Palmi V PV Eiriksdottir Gudny G Newman Anne B AB Harris Tamara B TB van Buchem Mark A MA Gudnason Vilmundur V Launer Lenore J LJ
Neurobiology of aging 20080907 7
<h4>Objective</h4>To assess whether markers of micro- and macrostructural brain abnormalities are associated with slower gait in older men and women independent of each other, and also independent of health-related conditions and of behavioral, cognitive and peripheral function.<h4>Methods</h4>Magnetization transfer ratio [MTR], white matter hyperintensities [WMH], brain atrophy [BA] and brain infarcts [BI] were measured in 795 participants of the AGES-Reykjavik Study cohort (mean 75.6 years, 58 ...[more]
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