Ontology highlight
ABSTRACT:
SUBMITTER: Galindo CL
PROVIDER: S-EPMC2873655 | biostudies-literature | 2010
REPOSITORIES: biostudies-literature
Galindo Cristi L CL Sha Jian J Moen Scott T ST Agar Stacy L SL Kirtley Michelle L ML Foltz Sheri M SM McIver Lauren J LJ Kozlova E V EV Garner Harold R HR Chopra Ashok K AK
Comparative and functional genomics 20100519
Braun/murein lipoprotein (Lpp) is involved in inflammatory responses and septic shock. We previously characterized a Deltalpp mutant of Yersinia pestis CO92 and found that this mutant was defective in surviving in macrophages and was attenuated in a mouse inhalation model of plague when compared to the highly virulent wild-type (WT) bacterium. We performed global transcriptional profiling of WT Y. pestis and its Deltalpp mutant using microarrays. The organisms were cultured at 26 and 37 degrees ...[more]