Ontology highlight
ABSTRACT:
SUBMITTER: de Jong EM
PROVIDER: S-EPMC2874026 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Current gastroenterology reports 20100601 3
Esophageal atresia and tracheoesophageal fistula (EA/TEF) are major congenital malformations affecting 1:3500 live births. Current research efforts are focused on understanding the etiology of these defects. We describe well-known animal models, human syndromes, and associations involving EA/TEF, indicating its etiologically heterogeneous nature. Recent advances in genotyping technology and in knowledge of human genetic variation will improve clinical counseling on etiologic factors. This review ...[more]