Ontology highlight
ABSTRACT:
SUBMITTER: Terracciano A
PROVIDER: S-EPMC2874623 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Terracciano A A Sanna S S Uda M M Deiana B B Usala G G Busonero F F Maschio A A Scally M M Patriciu N N Chen W-M WM Distel M A MA Slagboom E P EP Boomsma D I DI Villafuerte S S Sliwerska E E Burmeister M M Amin N N Janssens A C J W AC van Duijn C M CM Schlessinger D D Abecasis G R GR Costa P T PT
Molecular psychiatry 20081028 6
Personality traits are summarized by five broad dimensions with pervasive influences on major life outcomes, strong links to psychiatric disorders and clear heritable components. To identify genetic variants associated with each of the five dimensions of personality we performed a genome-wide association (GWA) scan of 3972 individuals from a genetically isolated population within Sardinia, Italy. On the basis of the analyses of 362 129 single-nucleotide polymorphisms we found several strong sign ...[more]