Ontology highlight
ABSTRACT:
SUBMITTER: Swinnen SG
PROVIDER: S-EPMC2875419 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Swinnen Sanne G SG Dain Marie-Paule MP Aronson Ronnie R Davies Melanie M Gerstein Hertzel C HC Pfeiffer Andreas F AF Snoek Frank J FJ Devries J Hans JH Hoekstra Joost B JB Holleman Frits F
Diabetes care 20100303 6
<h4>Objective</h4>To determine whether glargine is noninferior to detemir regarding the percentage of patients reaching A1C <7% without symptomatic hypoglycemia <or=3.1 mmol/l.<h4>Research design and methods</h4>In this 24-week trial, 973 insulin-naive type 2 diabetic patients on stable oral glucose-lowering drugs with A1C 7.0-10.5% were randomized to glargine once daily or detemir twice daily. Insulin doses were systematically titrated. RESULTS 27.5 and 25.6% of patients reached the primary out ...[more]