Optimal definitions for abdominal obesity and the metabolic syndrome in Andean Hispanics: the PREVENCION study.
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ABSTRACT: Objective
We aimed to establish optimal definitions for abdominal obesity and metabolic syndrome (MetS) among Andean adults.Research design and methods
Among 1,448 Andean adults, we assessed the relationship between waist circumference and subclinical vascular disease assessed by carotid intima-media thickness (cIMT) and manifest cardiovascular disease (M-CVD).Results
Optimal waist circumference cutoffs to classify individuals with abnormal cIMT or M-CVD were >97 and >87 cm in men and women, respectively. With these cutoffs, there was substantial disagreement between the original American Heart Association/National Heart, Lung and Blood Institute (AHA/NHLBI) and the recently updated MetS definition, particularly among men (kappa = 0.85). Subjects with MetS identified by the updated definition but not meeting the original AHA/NHLBI MetS criteria demonstrated significantly increased cIMT (P < 0.001) compared with subjects who did not meet the MetS criteria by either definition.Conclusions
Our findings support the use of ethnic-specific waist circumference cutoffs and the updated MetS definition in Andean adults.
SUBMITTER: Medina-Lezama J
PROVIDER: S-EPMC2875461 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Publications
Optimal definitions for abdominal obesity and the metabolic syndrome in Andean Hispanics: the PREVENCION study.
Medina-Lezama Josefina J Pastorius Catherine A CA Zea-Diaz Humberto H Bernabe-Ortiz Antonio A Corrales-Medina Fernando F Morey-Vargas Oscar Leopoldo OL Chirinos Diana Andrea DA Muñoz-Atahualpa Edgar E Chirinos-Pacheco Julio J Chirinos Julio Alonso JA
Diabetes care 20100303 6
<h4>Objective</h4>We aimed to establish optimal definitions for abdominal obesity and metabolic syndrome (MetS) among Andean adults.<h4>Research design and methods</h4>Among 1,448 Andean adults, we assessed the relationship between waist circumference and subclinical vascular disease assessed by carotid intima-media thickness (cIMT) and manifest cardiovascular disease (M-CVD).<h4>Results</h4>Optimal waist circumference cutoffs to classify individuals with abnormal cIMT or M-CVD were >97 and >87 ...[more]
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