Ontology highlight
ABSTRACT:
SUBMITTER: Anderson CT
PROVIDER: S-EPMC2876193 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Anderson Charles T CT Sheets Patrick L PL Kiritani Taro T Shepherd Gordon M G GM
Nature neuroscience 20100502 6
The mammalian motor system is organized around distinct subcortical subsystems, suggesting that the intracortical circuits immediately upstream of spinal cord and basal ganglia might be functionally differentiated as well. We found that the main excitatory pathway in mouse motor cortex, layer 2/3-->5, is fractionated into distinct pathways targeting corticospinal and corticostriatal neurons, which are involved in motor control. However, connections were selective for neurons in certain sublayers ...[more]