A unique adolescent response to reward prediction errors.
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ABSTRACT:
SUBMITTER: Cohen JR
PROVIDER: S-EPMC2876211 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Publications
A unique adolescent response to reward prediction errors.
Cohen Jessica R JR Asarnow Robert F RF Sabb Fred W FW Bilder Robert M RM Bookheimer Susan Y SY Knowlton Barbara J BJ Poldrack Russell A RA
Nature neuroscience 20100516 6
Previous work has shown that human adolescents may be hypersensitive to rewards, but it is not known which aspect of reward processing is responsible for this. We separated decision value and prediction error signals and found that neural prediction error signals in the striatum peaked in adolescence, whereas neural decision value signals varied depending on how value was modeled. This suggests that heightened dopaminergic prediction error responsivity contributes to adolescent reward seeking. ...[more]
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