Ontology highlight
ABSTRACT:
SUBMITTER: Bar KJ
PROVIDER: S-EPMC2876625 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Bar Katharine J KJ Li Hui H Chamberland Annie A Tremblay Cecile C Routy Jean Pierre JP Grayson Truman T Sun Chuanxi C Wang Shuyi S Learn Gerald H GH Morgan Charity J CJ Schumacher Joseph E JE Haynes Barton F BF Keele Brandon F BF Hahn Beatrice H BH Shaw George M GM
Journal of virology 20100407 12
Recent studies indicate that sexual transmission of human immunodeficiency virus type 1 (HIV-1) generally results from productive infection by only one virus, a finding attributable to the mucosal barrier. Surprisingly, a recent study of injection drug users (IDUs) from St. Petersburg, Russia, also found most subjects to be acutely infected by a single virus. Here, we show by single-genome amplification and sequencing in a different IDU cohort that 60% of IDU subjects were infected by more than ...[more]