Ontology highlight
ABSTRACT:
SUBMITTER: Johnstone S
PROVIDER: S-EPMC2878191 | biostudies-literature | 2009
REPOSITORIES: biostudies-literature
International review of cell and molecular biology 20090101
Intercellular channels formed by connexin proteins play a pivotal role in the direct movement of ions and larger cytoplasmic solutes between vascular endothelial cells, between vascular smooth muscle cells, and between endothelial and smooth muscle cells. Multiple genetic and epigenetic factors modulate connexin expression levels and/or channel function, including cell-type-independent and cell-type-specific transcription factors, posttranslational modifications, and localized membrane targeting ...[more]