Ontology highlight
ABSTRACT:
SUBMITTER: Li L
PROVIDER: S-EPMC2879357 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Li Lenong L Cheng Ninghui N Hirschi Kendal D KD Wang Xiaoqiang X
Acta crystallographica. Section D, Biological crystallography 20100515 Pt 6
Monothiol glutaredoxins (Grxs) play important roles in maintaining redox homeostasis in living cells and are conserved across species. Arabidopsis thaliana monothiol glutaredoxin AtGRXcp is critical for protection from oxidative stress in chloroplasts. The crystal structure of AtGRXcp has been determined at 2.4 A resolution. AtGRXcp has a glutaredoxin/thioredoxin-like fold with distinct structural features that differ from those of dithiol Grxs. The structure reveals that the putative active-sit ...[more]