Ontology highlight
ABSTRACT:
SUBMITTER: Johnson BA
PROVIDER: S-EPMC2880217 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Johnson B A BA Wang J J Taylor E M EM Caillier S J SJ Herbert J J Khan O A OA Cross A H AH De Jager P L PL Gourraud P-A F PA Cree B C A BC Hauser S L SL Oksenberg J R JR
Genes and immunity 20091029 4
Multiple sclerosis (MS) is an autoimmune demyelinating disease characterized by complex genetics and multifaceted gene-environment interactions. Compared to whites, African Americans have a lower risk for developing MS, but African Americans with MS have a greater risk of disability. These differences between African Americans and whites may represent differences in genetic susceptibility and/or environmental factors. SNPs from 12 candidate genes have recently been identified and validated with ...[more]