Ontology highlight
ABSTRACT:
SUBMITTER: Lopes AM
PROVIDER: S-EPMC2884166 | biostudies-literature | 2010 May
REPOSITORIES: biostudies-literature
BMC molecular biology 20100507
<h4>Background</h4>The Y chromosome of mammals is particularly prone to accumulate genes related to male fertility. However, the high rate of molecular evolution on this chromosome predicts reduced power to the across-species comparative approach in identifying male-specific genes that are essential for sperm production in humans. We performed a comprehensive analysis of expression of Y-linked transcripts and their X homologues in several human tissues, and in biopsies of infertile patients, in ...[more]