Multiple recombinant dengue type 1 viruses in an isolate from a dengue patient.
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ABSTRACT: Between 2000 and 2004, dengue virus type 1 (DENV-1) genotypes I and II from Asia were introduced into the Pacific region and co-circulated in some localities. Envelope protein gene sequences of DENV-1 from 12 patients infected on the island of New Caledonia were obtained, five of which carried genotype I viruses and six, genotype II viruses. One patient harboured a mixed infection, containing viruses assigned to both genotypes I and II, as well as a number of inter-genotypic recombinants. This is the first report of a population of dengue viruses isolated from a patient containing both parental and recombinant viruses.
SUBMITTER: Aaskov J
PROVIDER: S-EPMC2884982 | biostudies-literature |
REPOSITORIES: biostudies-literature
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