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Paltolides A--C, anabaenopeptin-type peptides from the palau sponge Theonella swinhoei.

ABSTRACT: Three new anabaenopeptin-like peptides, named paltolides A-C, were isolated from a deep-water specimen of the marine sponge Theonella swinhoei from Palau. Paltolides belong to a rare subgroup of sponge-derived anabaenopeptins that have in common a C-terminal tryptophan residue linked to the epsilon-amine of a lysine bearing a d configuration. The structures of paltolides A-C were determined by NMR and tandem MS techniques. Paltolide A is the first anabaenopeptin structure where a non-N-methylated amino acid precedes the C-terminal residue.

SUBMITTER: Plaza A

PROVIDER: S-EPMC2885440 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature

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Paltolides A--C, anabaenopeptin-type peptides from the palau sponge Theonella swinhoei.

Plaza Alberto A Keffer Jessica L JL Lloyd John R JR Colin Patrick L PL Bewley Carole A CA

Journal of natural products 20100301 3

Three new anabaenopeptin-like peptides, named paltolides A-C, were isolated from a deep-water specimen of the marine sponge Theonella swinhoei from Palau. Paltolides belong to a rare subgroup of sponge-derived anabaenopeptins that have in common a C-terminal tryptophan residue linked to the epsilon-amine of a lysine bearing a d configuration. The structures of paltolides A-C were determined by NMR and tandem MS techniques. Paltolide A is the first anabaenopeptin structure where a non-N-methylate ...[more]

PMID: 20078073

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New Theonellapeptolides from Indonesian Marine Sponge <i>Theonella swinhoei</i> as Anti-Austerity Agents.

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Theonella swinhoei

Project description:Theonella swinhoei overview

| PRJNA1084994 | ENA

Theonellamide G, a potent antifungal and cytotoxic bicyclic glycopeptide from the Red Sea marine sponge Theonella swinhoei.

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A New N-Acyl Homoserine Lactone Synthase in an Uncultured Symbiont of the Red Sea Sponge Theonella swinhoei.

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