Ontology highlight
ABSTRACT:
SUBMITTER: Abend JR
PROVIDER: S-EPMC2887564 | biostudies-literature | 2009 May
REPOSITORIES: biostudies-literature
Abend Johanna R JR Joseph Amy E AE Das Dweepanita D Campbell-Cecen Deniz B DB Imperiale Michael J MJ
The Journal of general virology 20090304 Pt 5
The early region of BK virus (BKV) is known to encode two well-characterized tumour (T) antigens, large T antigen (TAg) and small T antigen (tAg). In this study, we provide evidence of a third early BKV mRNA that codes for an additional early region product with an apparent molecular mass of 17-20 kDa. This truncated form of TAg (truncTAg) is expressed from an alternatively spliced mRNA that is derived from the excision of a second intron from the mRNA encoding TAg. The first 133 aa of truncTAg ...[more]